Nematicides may affect nontarget organisms which are keeping nematodes, plant pathogens or insects under control.
A broad spectrum product (e.g. methyl bromide) may kill other pathogens in addition to nematodes and improve yields beyond those obtainable with a nematicide alone.
Some chemicals applied for insect control within a plot may also be nematicidal.
Field trials can offer opportunities for illustrating to growers the effectiveness of various management techniques.