LUNG:

MOUSE TUMOR TYPE		DOSE (MG/KG/DAY)	DOSE (MG/KG/DAY)	DOSE (MG/KG/DAY)
	SEX	0	25	50	Historical Incidence
adenomas	M	1/50	11/50	9/50
		2%	22%	18%	9.10%
	F	0/50	3/50	8/50
		0%	6%	16%*	3.30%
carcinomas	M	0/50	2/50	3/50
		0%	4%	6%	5.40%
	F	2/50	1/50	0/50
		4%	2%	0%	1.50%
adenomas and carcinomas combined	M	1/50	13/50	12/50
		2%	26%	24%	14.30%
	F	2/50	4/50	8/50
		4%	8%	16%*	4.70%

* = p < 0.5, Fisher's Exact Test. The Fisher's Exact Test was not performed in males due to an insufficient number of males in the control group.

Even without exposure to the chemical, two female mice developed carcinomas of the lung compared to one for low dosage and zero for high dosage mice. However, when the number of adenomas (abnormal growths) was combined with the nonexistent carcinomas, a statistically significant number of carcinomas was declared.

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